-3-azaspiro[5.5]undecan-9-yl)

-3-azaspiro[5.5]undecan-9-yl) - Names and Identifiers

Name	2-(9-tert-butoxycarbonyl-9-azaspiro[5.5]undecan-3-yl)acetic acid
Synonyms	2-(3-(tert-Butoxycarbonyl) -3-azaspiro[5.5]undecan-9-yl) 3-BOC-3-azaspiro[5.5]undecan-9-acetic acid 3-[(tert-Butoxy)carbonyl]-3-azaspiro[5.5]undecane-9-acetic acid 2-(9-tert-butoxycarbonyl-9-azaspiro[5.5]undecan-3-yl)acetic acid 2-(3-(TERT-BUTOXYCARBONYL)-3-AZASPIRO[5.5]UNDECAN-9-YL)ACETIC ACID 2-(3-(tert-butoxycarbonyl)-3-azaspiro[5.5]undecane-9-yl)acetic acid 3-Azaspiro[5.5]undecane-9-acetic acid, 3-[(1,1-diMethylethoxy)carbonyl]- 9-CarboxyMethyl-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester
CAS	952480-32-9
InChI	InChI=1/C17H29NO4/c1-16(2,3)22-15(21)18-10-8-17(9-11-18)6-4-13(5-7-17)12-14(19)20/h13H,4-12H2,1-3H3,(H,19,20)

-3-azaspiro[5.5]undecan-9-yl) - Physico-chemical Properties

Molecular Formula	C17H29NO4
Molar Mass	311.42
Density	1.12g/cm³
Boling Point	452.7°C at 760 mmHg
Flash Point	227.6°C
Vapor Presure	1.86E-09mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.519

-3-azaspiro[5.5]undecan-9-yl) - Introduction

2-([5.5]undecan-3-yl)acetic acid is an organic compound commonly abbreviated as Boc-NASU. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless to slightly yellow solid
-Chemical formula: C18H31NO5
-Molecular weight: 345.5g/mol
-melting point: 77-79 ℃
-Boiling point: 456.2 ℃
-Solubility: Soluble in ethanol, acetone and dimethyl sulfoxide, slightly soluble in water

Use:
-In organic synthesis, Boc-NASU are often used as reagents to protect amino acids in polypeptides or proteins.
-It can form Boc-amino acid ester by reacting with amino acid, thereby protecting the active amino group.
- Boc-NASU can also be used to synthesize other nitrogen-containing organic compounds.

Preparation Method:
-The preparation of Boc-NASU is usually carried out by reacting aminospiranone with tri-tert-butyl phosphonic acid oxide (TBOP) under the catalysis of a base to obtain the Boc-NASU precursor compound.
-Then, the precursor compound is reacted with acetic anhydride to obtain the final product Boc-NASU.

Safety Information:
- Boc-NASU may be harmful to health, so safe operating procedures should be followed when using it.
-It is an irritating compound that may cause irritation to the eyes, skin and respiratory tract.
-Use with appropriate personal protective equipment, such as lab gloves and goggles.
-Avoid inhalation, ingestion, or contact with skin. If contact occurs, flush the affected area with plenty of water and seek medical attention.
-storage should avoid high temperature and open fire, it is recommended in a cool, dry place sealed preservation.

Last Update：2024-04-10 22:29:15